ภาควิชาโสต ศอ นาสิกวิทยา

Objectives

To investigate the effects of a 3-month OMT program on PAP pressure, as determined by the auto-adjusting positive airway pressur .

Objectives

To investigate the effects of a 3-month OMT program on PAP pressure, as determined by the auto-adjusting positive airway pressure (APAP) algorithm, including maximum pressure, 95th percentile pressure, mean pressure, and com-pliance in patients with OSA.

Methods

A prospective cohort intervention study was conducted at Naresuan University Hospital involving 70 OSA patients aged 18–80 years on APAP therapy. Participants underwent a 3-month OMT program, performing twice-daily exercises targeting the palate, tongue, and facial muscles. APAP pressure data and compliance were collected before and after the intervention. Statistical analysis was performed using a multivariate multilevel Gaussian regression model to assess changes in pressure over time. APAP compliance was analyzed using student’s t-test and the signed-rank test, with statistical signifi[1]cance set at P<0.05

Results

Statistically significant reductions in all APAP parameters were observed subsequent to OMT: mean pressure (-0.50 cmH2O, 95% CI: -0.66, -0.32), 95th percentile pressure (-0.68 cmH2O, 95% CI: -0.89, -0.47), and maximum pressure (-1.14 cmH2O, 95% CI: -1.47, -0.80). Additionally, APAP adherence significantly improved, with average nightly usage increasing from 5.86±1.27 h to 6.42±1.23 h.

Conclusion

A 3-month OMT program effectively reduced APAP pressure requirements and improved adherence in OSA patients. While pre-OMT data suggested a gradual increase in APAP pressure needs over time, OMT counteracted this trend by addressing both anatomical and non-anatomical factors. These findings support OMT as a valuable adjunctive therapy for enhancing PAP therapy outcomes.